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Sports Med. 2007;37(3):225-64.
The influence of frequency, intensity, volume and mode of strength training on whole muscle cross-sectional area in humans.
Wernbom M, Augustsson J, Thomee R.
Lundberg Laboratory for Human Muscle Function and Movement Analysis, Department of Orthopaedics, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden.
Strength training is an important component in sports training and rehabilitation. Quantification of the dose-response relationships between training variables and the outcome is fundamental for the proper prescription of resistance training. The purpose of this comprehensive review was to identify dose-response relationships for the development of muscle hypertrophy by calculating the magnitudes and rates of increases in muscle cross-sectional area induced by varying levels of frequency, intensity and volume, as well as by different modes of strength training.Computer searches in the databases MEDLINE, SportDiscus((R)) and CINAHL((R)) were performed as well as hand searches of relevant journals, books and reference lists. The analysis was limited to the quadriceps femoris and the elbow flexors, since these were the only muscle groups that allowed for evaluations of dose-response trends. The modes of strength training were classified as dynamic external resistance (including free weights and weight machines), accommodating resistance (e.g. isokinetic and semi-isokinetic devices) and isometric resistance. The subcategories related to the types of muscle actions used. The results demonstrate that given sufficient frequency, intensity and volume of work, all three types of muscle actions can induce significant hypertrophy at an impressive rate and that, at present, there is insufficient evidence for the superiority of any mode and/or type of muscle action over other modes and types of training. Tentative dose-response relationships for each variable are outlined, based on the available evidence, and interactions between variables are discussed. In addition, recommendations for training and suggestions for further research are given.
Excerpts From the Discussion
Frequency
Quote:
For quadriceps training with dynamic external resistance, the largest rate of gain in CSA (0.55% per day) was noted in the study[84] with the greatest training frequency (12 sessions per week). However, it should be noted that (i) this study lasted for only 2 weeks; (ii) the intensity was 20% of 1RM; and (iii) the training was performed in combination with partial vascular occlusion. Therefore, the results from this study should be viewed with caution when considering the application of extremely high frequencies in more conventional training. Furthermore, it is interesting to note that there was no training difference in the mean rates of increase in CSA between two and three sessions per week for DER.
For elbow flexor training with dynamic external resistance, the greatest rate of increase in CSA (0.59% per day; 17.7% total increase in CSA) was observed in a study[128] with a frequency of four times a week. The second, third, fourth highest increase in CSA rates noted were 0.42%, 0.38% and 0.32% per day, respectively. These three studies[125,126,132] used a frequency of three times per week. However, with the exception of these three studies, the average values suggest that there is relatively little difference between training the elbow flexors two or three times per week, in terms of the rate of increase in CSA (0.18% per day for both frequencies).
The results of Vikne et al.[79] and Wirth et al.[134] are remarkably similar despite using different muscle groups and training modes. In both reports, two and three sessions per week yielded almost twice the
increase in muscle CSAwhen compared with one session, with no apparent further advantage for three versus two sessions.