Strixaderm-MD is the only dermal agent that I've known to work quickly and effectively. Only problem is, it's about $80 for a 2-3 month supply. Shea Butter (and I suppose Vitamin E Cocoa Butter) also works well, but because thye don't contain actual collagen or elastin (I believe they just promote skin health rather than provide the actual raw materials used in skin repair) they're quite a bit slower-working.