Losing the fat stored in the thighs depends heavily on nutrition. In addition cardiovascular exercises such as running are very good for keeping the thighs from gaining fat while still losing lots of it.
Increase your protein intake - eggs, lean meat, chicken, fish, etc. All these will help support your metabolism.
At the same time eliminate junk food from your meals.
All this will make a huge difference quickly. Once you start losing the fat, squats, lunges, leg curls, stiff-legged dead lifts, leg extensions, and calf raises will all help you tone your legs.