depends on the goal, and how many 'more reps' you mean.
10 reps is going to build more muscle size, but less muscle strength
6 reps is going to build more muscle strength, but less muscle size
16 reps is going to build muscle endurance, but not much strength or size, and it sure as hell doesn't "tone" the muscle.
the number of sets you perform depends on total workload and how your whole program is designed.