dbutterfield
New member
Steve,
Happy Friday, Have a great day and weekend.
David
Happy Friday, Have a great day and weekend.
David
Journey, Not A Destination
- Thread starter Steve
- Start date
Britta Bear
New member
Good Morning Steve!
Curvie Girlie
New member
Morning Steve! Have a great day helping people out!!!
Hiya Brit!
What links are you referring to? I hand out so many links I can't remember.
wrt to protein resistance, honestly, I haven't done research on that. Never felt the need since I have encountered anyone that would lead me to believe they were resistant to protein.
What exactly are you referring to? Can you provide me with some literature to read?
Morning Val. I didn't help anyone yesterday. Spent the day watching my friends play baseball in their league championship. It was a nice break, aside from the cold and rain.
Did they win? 
Steve as a cheerleader -that's cute did you shake your pom poms?
Steve as a cheerleader -that's cute
did you shake your pom poms?
Did they win?
Steve as a cheerleader -that's cute
They did win.
I did not have pom poms.
YAY!!!
/me turns a cartwheel
/me turns a cartwheel
that was a yay for the winning - not for you not having pom poms - you should seriously consider getting a pair of pom poms they're all kinds of sassy fun
they're all kinds of sassy fun Lol, hey I found somthing you don't know!
Ob protein, other wise known as "leptin". What are your thoughts on "Leptin" resistance in the overweight population?
that was a yay for the winning - not for you not having pom poms - you should seriously consider getting a pair of pom poms
Absolutely not.
BerdieForJosh
New member
Ho Steve,
Hi There Steve,
Nicw job!! I am a newbie at working out-- I thought it meant taking a long walk-Boy was I ever wrong.. but looking at what your committment has done for your body; well its inspiring to say the least!
If any of you can suggest some pointers for me for losing 15 pounds I'd appreciate it- My problem is my thyroid- it's like a turtles very slow.. I take meds to regulate it and it does but taking weight off is a lifelong struggle-
Thanks,
Berdie
Hi There Steve,
Nicw job!! I am a newbie at working out-- I thought it meant taking a long walk-Boy was I ever wrong.. but looking at what your committment has done for your body; well its inspiring to say the least!
If any of you can suggest some pointers for me for losing 15 pounds I'd appreciate it- My problem is my thyroid- it's like a turtles very slow.. I take meds to regulate it and it does but taking weight off is a lifelong struggle-
Thanks,
Berdie
No you didn't. Haha, sorry.
You originally wrote op protein. Not "OB."
That's why we had our wires crossed.
And I'm used to referring to this as leptin resistance, not protein resistance as you stated originally.
So the question is wrt to leptin resistance commonly found in obese populations.
For those of us who are not in the know, leptin is directly correlated with body fat. As body fat increases, so does leptin levels.
Logically then, it seems as if there should never be a problem with starvation signaling since leptin levels are adequate in the obese. Unfortunately, leptin in and of itself, promotes leptin resistance and such resistance compounds the metabolic impact of diet-induced obesity.
So do I think it's as impacting as insulin resistance? In a nutshell, yes. I think there's still much to know and learn from science yet on this subject.... but I certainly think it's a contributing factor (negative) associated with obesity.
I think leptin resistance is the primary reason why, even with some obese individuals I've helped or am helping, that their weight loss plateaus. I mean, why on earth would their bodies not give up fat? Everything is in place physiologically and biologically to let the body *know* that it's well-fed when someone is obese. Yet, even with meticulous diet and exercise, I will still see someone stall out.
Leptin resistance, although plenty of leptin is present, leads to the same *starvation signaling* that low leptin levels associate with.
A lot of this neurohormonal stuff is beyond me. It's certainly fascinating to me and I'll continue to stay on top of it research-wise. I'd like to pick Lyle's brain on this too.... I've been meaning to. Just haven't gotten around to doing so yet.
It's pretty evident empirically though, that dieting breaks will be required no matter what. Lean trying to get very lean.... you'll most likely need to incorporate refeeds. Obese trying to get *normal*, you'll probably have to take breaks back up to maintenance.
As fat loss happens, leptin sensitivity will improve.
It's all part of that *touch & feel" process.
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Hi There Steve,
Nicw job!! I am a newbie at working out-- I thought it meant taking a long walk-Boy was I ever wrong.. but looking at what your committment has done for your body; well its inspiring to say the least!
If any of you can suggest some pointers for me for losing 15 pounds I'd appreciate it- My problem is my thyroid- it's like a turtles very slow.. I take meds to regulate it and it does but taking weight off is a lifelong struggle-
Thanks,
Berdie
What's up Berdie, thanks for the kind words!
I'd really suggest starting out by reading the stickies located at the top of the various sub-forums here. Specifically, you should read the "words of wisdom" thread. You'll learn a lot.
What do you do now in terms of exercise and what's the diet look like?
Lol, damn man I thought I finally had you...
Actually you and I see eye to eye on this subject. Its hard to have a debate on something when yours and my opinions on many matters are one in the same.
Recently the hormanal (in essense the entire biological aspect really )of weight loss has become an interest of mine. Any other materials you got for me?
Question, a 300 pound person goes on a 1,500Kcal diet. Approximately 1,000calorie deficient. The initial weight lossed in the first week should be mostly comprised of water. So leptin levels should remain stable at this time. By the second week and further bodily lipid mass (BLM) loss is the greater %. So, its at this time leptin levels begin to fall in proportion that BLM does. At this point due to leptin resistance the body than sees there is not enough circulating, when there actually is. Than the body begins to enter "starvation mode". Weight loss begins to slow so we increase the calorie intake for a week to 2,500. Once this week ends we begin a diet again of 1,500Kcall. The initial weight loss values I would assume to be water/glycogen as in the starting week. As you can see the cycle than can begin to repeat. However, with each "cycle" I would assume leptins receptors are regaining or becoming more "sensitive" thus the lower amount is no longer triggering the dreaded "StarvationM". So, It seems to me that weight loss does in fact reverse, at least to some extent, Ob protein sensitivity. Because, re-feeds seem very affective at breaking plateaus that are likely due to leptin Resistance. Although, for the people that tend to regain weight quickly after weight loss goal is met. Is it not possible they did not correctly "retrain" leptin receptors during the weight loss? Perhaps not including a re-feed when they possibly should had?
Of course thats ignoring possible habtual eating patterns (aswell as other contributuers/possible causes) simply come back. And maybe leptins resistance can only be temporarily "corrected" which might explain why long term weight loss is so rare.
Hope that made sense
. I'm in a slight rush so had to type it up real fast.
Lol, damn man I thought I finally had you...
Actually you and I see eye to eye on this subject. Its hard to have a debate on something when yours and my opinions on many matters are one in the same.
Agreed.
And no need for a debate. Discussion is just as good as debate IMO. I can say I've had more "enlightenment" while discussing topics with with someone on the web when we see eye to eye. More so than during many of my debates with people on the web. Haha, and there's been a many!
Thinking, in whatever context, is always good.
It's actually a huge interest of mine too. I wish more research was done on it. Did you read the leptin links I posted a few pages back in my journal?
Aside from squirming through high level text books and digging through research, there are no good books that I'm familiar with on the subject.
On paper, it's easy. Reduce leptin levels to increase leptin sensitivity. And for outside readers (although I doubt there are many who care, lol) remember, we are speaking wrt to obese populations here!
There's no real way right now to tell if someone is leptin resistant. But generally, if you don't have too much of an issue staying lean, chances are good you aren't in the boat of leptin resistance. And I think Lyle even said himself..... if you are at all fat, you probably have some degree of leptin resistance.
The situation you outlined here is a funny one. People, even trainers, seem to blame the *starvation mode* for putting on fat. That's not how it works.
You diet.
You lose fat.
Leptin falls and various signaling occurs. One of them is a reduction in metabolism.
However, you are still in a deficit. Sure, it's a smaller deficit. Heck, you might even get close to a new, lower maintenance.
No studies show where metabolism drops greater than the deficit. Not even in the extreme Minnesota Starvation Experiment.
If you find yourself getting fat, that's b/c you started eating more. It makes sense b/c when people start seeing results come to a crawl, they tend to give up.
And this is why planned refeeds or maintenance-feeds should be not only implemented.... but also UNDERSTOOD. If they understand why, they'll understand that metabolic rate is a dynamic phenomenon and it will slow at times during a diet plan. And b/c of this, your diet plan has to be dynamic in nature as well. Obese or skinny.
Will leptin resistance go away? It hasn't been studied. I'm inclined to say no. Will leptin sensitivity be improved with the inclusion of sound lifestyle choices? I certainly believe so.
I've got a ton of studies on leptin that you could easily find yourself on pubmed.... but none tell a whole lot more than what we're discussing here.
dbutterfield
New member
Hello Steve,
It sounds like you had a good weekend. I always enjoy reading your journal as there is always good reading to be had. Thank you for everything!
David
It sounds like you had a good weekend. I always enjoy reading your journal as there is always good reading to be had. Thank you for everything!
David