Tumor Removal Through Bone Cancer Treatment Without Losing the Limb: Is It Possible?

drfaizan

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Bone cancer diagnosis might make a person imagine the worst-case scenario. The fear gets even more intense when it comes to the location of the tumor, which is usually an arm or a leg. The main concern in this case will be: “Is the whole limb going to be amputated?” This situation might be extremely difficult from an emotional point of view, as well as from a practical one, since routine actions start becoming unpredictable for the patient.

Luckily, the treatment for bone cancer has advanced a lot compared to previous generations, and limb amputation is not the only type of surgery anymore for some patients. Bone cancer treatment without amputation is possible, and it takes place in 90% of all cases. This blog explains the procedure of tumor removal through bone cancer treatment without amputation, so that patients can confidently fight bone cancer.

Understanding Bone Tumors​


The primary bone cancers include osteosarcoma, Ewing sarcoma, and chondrosarcoma, which develop within the body of the bone itself. Amputation was thought to be the best way to guarantee removal of all the cancerous cells in the past, but patients had to lose a whole leg to keep themselves alive.

Nowadays, through limb-salvage surgery (also referred to as limb-sparing surgery), this has become a different scenario altogether. The goals of current tumor removal through bone cancer treatment can be put into two categories:

  • Ensuring that the patient's life is saved by completely removing the cancer
  • Protecting the physical structure and appearance of the limb

What Does Tumor Removal Through Bone Cancer Treatment Involve?​


Limb preservation surgery is a complex and highly technical procedure performed by a specialized interdisciplinary team. Limb salvage surgery depends upon removal of the tumor with clear margins, followed by reconstruction of the damaged skeleton.

1. Pre-Surgical Medical Treatments​


Prior to the surgery, patients usually receive treatments such as chemotherapy or radiation therapy. In this case, shrinking the tumor mass, defining its boundaries, and killing any microscopic cancer cells that may be floating around near the margins are achieved.

2. Wide Local Excision Surgery​


As part of the surgery, the orthopedic surgeon will perform a wide resection. During the resection, the orthopedic surgeon will remove not only the tumor but also a margin of healthy bone and soft tissue surrounding the mass. Clear margins mean no cancer cells are left, therefore reducing the chance of local recurrence.

3. Structural Reconstruction​


After tumor removal through bone cancer treatment, an orthopedic oncology reconstructive surgeon will reconstruct the damaged segment of the skeleton. Here comes the role of advanced biotechnology and surgery:

  • Metallic Endoprosthesis (Endoprosthetics): Durable implants made of titanium or cobalt-chrome alloys take the place of lost bone structures or joints (such as knee, shoulder, hip joints, etc.). Growing children could benefit from bionic extendable implants which could be expanded externally via magnetic manipulation.

  • Autograft: Bone tissue harvested from some other bone structure of the patient (such as fibula or pelvis) is grafted into place to fill the void.

  • Allograft: Sterilized bone tissue obtained from a tissue bank and grafted into place to become a biological scaffold which eventually becomes integrated within the bone tissue of the recipient.

  • Composite Reconstruction: Combination of donor bone tissue and metal implants which are intended to give mechanical support right away.

How Do Doctors Decide Whether the Limb Can Be Saved?​


Limb-sparing surgery is not based on appearance alone. A limb may look relatively normal from the outside while the tumor has already reached structures that are essential for its function. Doctors generally consider several factors before deciding the type of bone cancer treatment:

  • Tumor location: A tumor located in a surgically accessible site could be easily removed with preservation of the limb.
  • Tumor size: Larger Tumors are likely to contain more tissue around them, hence making reconstruction harder.
  • Blood vessels and nerves near the site: Extensive involvement of the major blood vessels or nerves makes preservation of the limb impossible.
  • Stage of cancer: The existence of the cancer at another part of the body changes the whole approach towards its treatment.
  • Response to chemotherapy: In cases such as osteosarcoma, the response of the tumor to the treatment prior to the surgery is a consideration.
  • The ability to remove the tumor with proper margins: The surgeon needs to be able to do the operation with sufficient margin of normal tissue.
  • General status of the patient: The patient’s age, health status, and the ability to withstand the surgery are also important considerations.

According to the National Cancer Institute, about 80% of patients with extremity osteosarcoma may be treated with limb-sparing surgery.

Key Benefits of Limb Preservation for Patients​


Choosing the limb-saving option is very beneficial from both physical and psychological perspectives for the following reasons:

BenefitDetail
Retention of Body ImageThe retention of natural limbs builds self-respect and decreases psychological damage resulting from a drastic change in one’s physique.
Normal Movements and ReflexesPreservation of natural muscles, bones, and nerves ensures preservation of normal movements and reflexes.
Tumor Control for LifeWhen performed at oncology centers, the limb-saving technique is safe and has almost the same effectiveness as amputation.
Better Quality of LifePatients become more independent in terms of their physical abilities and face fewer social restrictions.
Confidence and IndependencePatients retain their physical independence and face fewer social restrictions.


Recovery from Limb-Sparing Surgery​


Recovery may take time, especially when there has been reconstruction of a large part of the bone and joints. At first, help will probably be needed when walking and carrying out normal daily tasks. Physiotherapy and rehabilitation may become important parts of the recovery process. It depends on where the surgery was carried out and what was reconstructed.

For example, surgery carried out around the knee joint may mean that the patient requires a rehabilitation program aimed at strengthening and improving mobility in the knee joint. Surgery done in the upper arm may require a different approach to rehabilitation.

Recovery thus does not only consist of allowing the surgical wound to heal. It also consists of gaining confidence to become healthy and cancer-free.

A Hopeful Horizon in Bone Oncology​


The diagnosis of bone cancer can be physically and emotionally challenging. However, it does not always mean amputation. With modern medical technology, doctors can often remove the tumor while preserving the affected limb. Surgery paired with tailor-made 3D-printed replacement parts and improved reconstructive procedures makes safe removal of the tumor possible without losing the limb.

Patients can now take advantage of consulting with a highly skilled orthopedic surgeon in order to make their way through this path successfully.
 
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