Study / Article - Muscle, Metabolism & Weight Loss

I read the below article on CNN Health this morning and I am now confused.:confused: The underlined statements from Dr. Ravussin directly conflict with what I have learned on this site regarding strength training to keep / build muscle in order to increase metabolism and lose fat. I initially lost 25 pounds last year by doing cardio only and eating a clean diet but with very little meat / protein. This past couple months, based on the advise from this site (which I appreciate), I have been doing much more weight lifting, very little cardio and eating a clean diet, but with much more meat / protein.
Since making this change I have not lost anymore fat, but have gained a bit of lean muscle mass. My goal is to lose the remaining 10 lbs of fat that I have, with or without any additional muscle gains.
Any comments or advise is appreciated.

Research adds to evidence that adding muscle mass does not boost metabolism:eek: • Dieting alone also did not appear to cause loss of muscle mass along with fat

WASHINGTON (Reuters) -- Eating less and exercising more are equally good at helping take off the pounds, U.S. researchers said Friday in a study that challenges many of the popular tenets of the multibillion dollar diet and fitness industry.

Tests on overweight people show that a calorie is just a calorie, whether lost by dieting or by running, they said.

They found there is no way to selectively lose belly fat, for instance, or trim thighs. And their carefully controlled study added to evidence that adding muscle mass does not somehow boost metabolism and help dieters take off even more weight.

"It's all about the calories," said Dr. Eric Ravussin of the Pennington Biomedical Research Center, part of Louisiana State University in Baton Rouge.

"So long as the energy deficit is the same, body weight, fat weight, and abdominal fat will all decrease in the same way."

Ravussin said the study, published in the Journal of Clinical Endocrinology & Metabolism, is one of the few done under controlled conditions that can actually demonstrate what happens to a human body while dieting and exercising.

Ravussin's team has been testing volunteers for another reason -- to see whether taking in fewer calories helps people live longer. Strict diets have been shown to help animals from worms to dogs live longer, but it takes longer to study monkeys and humans.

They tested 24 people, 12 who ate a calorie-restricted diet, and 12 who dieted and also exercised five times a week for six months.

The dieters ate 25 percent less than normal, while the exercisers reduced their calorie intake by 12.5 percent and increased their physical activity to lose an extra 12.5 percent in calories.

An additional 10 volunteers acted as controls. All food was provided by the university in carefully measured portions for most of the study.

The volunteers in both groups lost about 10 percent of their body weight, 24 percent of their fat mass, and 27 percent of their abdominal visceral fat. Visceral fat is packed in between the internal organs and is considered the most dangerous type of fat, linked with heart disease and diabetes.

The distribution of the fat on the body was not altered by either approach -- helping prove that there is no such thing as "spot reducing", Ravussin said in a telephone interview.

This suggests that "individuals are genetically programmed for fat storage in a particular pattern and that this programming cannot easily be overcome," he added.

Ravussin has published other studies that also dispute the idea that exercise builds muscle that helps people lose weight.:eek:

"If anything, highly trained people are highly efficient, so they burn fewer calories at rest," Ravussin said.:eek:

Dieting alone also did not appear to cause the volunteers to lose muscle mass along with fat, Ravussin's team found.:confused:

"There is a concept that if you exercise, you are going to lose less of your muscle," he said. But his team found no evidence this is true.:confused:

Ravussin believes exercise is crucial to health, however.

"For overall health, an appropriate program of diet and exercise is still the best," he said.

His team found some small suggestion that cutting 25 percent of calories by either diet or diet and exercise might extend life.

"We found that 2 of the biomarkers of aging were improved -- core temperature was 0.4 to 0.5 degrees C less," he said. "Insulin, which has been shown to be a biomarker of aging, was reduced," Ravussin said. That finding was published in the Journal of the American Medical Associaton last April.
 
They tested 24 people, 12 who ate a calorie-restricted diet, and 12 who dieted and also exercised five times a week for six months
.

Doing what though, what kind of exercise this is important.

The volunteers in both groups lost about 10 percent of their body weight, 24 percent of their fat mass, and 27 percent of their abdominal visceral fat. Visceral fat is packed in between the internal organs and is considered the most dangerous type of fat, linked with heart disease and diabetes.
No discussion about raise of LBM or muscle gain?

This suggests that "individuals are genetically programmed for fat storage in a particular pattern and that this programming cannot easily be overcome," he added.
Well yeah just stating it comes off where it wants to come off.


"If anything, highly trained people are highly efficient, so they burn fewer calories at rest," Ravussin said.

Obviously they are not testing Muscle oxygen uptake. Just BMR. Obviously someone who is trained has a lower BMR but that isn't the only role being played in metabolic transfer or energy usage.

Dieting alone also did not appear to cause the volunteers to lose muscle mass along with fat, Ravussin's team found.

How largely overweight were these subjects. Obese individuals almost never lose muscle in beginning stages.

"There is a concept that if you exercise, you are going to lose less of your muscle," he said. But his team found no evidence this is true.
Again what kind of exercise, how large were the subjects?

I am going to find this study to hopefully read the study details. I doubt very much that NIRcws was used as a valid method for quantitatively measuring exercising muscle metabolism or other muscle metabolic testing methods. It seems to me that BMR was left to stand alone in this, if that is the case then yes little difference is going to be shown towards favor of muscle.

This is a great study on Muscle metabolism, very detailed, very controlled. My point people is not all studies are created equal, and you have to be careful which ones you by into.
 
I'm so happy theleip put in the time to question the numerous leftout information in this short article. Especially when it comes to the lack of details on the exercises. The whole thing is so vague it barely even constitutes as a real report.

~Nicole
 
Thanks for the replies. I assume from your replies you disagree in general with the study / article.
Does this mean that you support the following:

1. Strength training is required to prevent muscle loss while in a calorie deficit.
2. Increase in LBM increases metabolism (BMR).

What causes the body to resort catabolism of muscle rather than stored fat?
Is muscle catabolism caused more by a 1) calorie deficit 2) lack of protein 3) lack of using/working the muscle or 4) all of these ?
 
Muscle does not speedd metabolism? Comments?

Ok, I found this article this morning and it just doesn't seem right. It would seem to indicate that it is equally easy to maintain muscle as it is to maintain fat and that denser muscle mass does not use more energy.


Diet, Exercise take off Equal Pounds, Study Finds
Reuters

WASHINGTON (Reuters) - Eating less and exercising more are equally good at helping take off the pounds, U.S. researchers said on Friday in a study that challenges many of the popular tenets of the multibillion dollar diet and fitness industry.

Tests on overweight people show that a calorie is just a calorie, whether lost by dieting or by running, they said.

They found there is no way to selectively lose belly fat, for instance, or trim thighs. And their carefully controlled study added to evidence that adding muscle mass does not somehow boost metabolism and help dieters take off even more weight.

"It's all about the calories," said Dr. Eric Ravussin of the Pennington Biomedical Research Center, part of Louisiana State University in Baton Rouge.

"So long as the energy deficit is the same, body weight, fat weight, and abdominal fat will all decrease in the same way."

Ravussin said the study, published in the Journal of Clinical Endocrinology & Metabolism, is one of the few done under controlled conditions that can actually demonstrate what happens to a human body while dieting and exercising.

Ravussin's team has been testing volunteers for another reason -- to see if taking in fewer calories helps people live longer. Strict diets have been shown to help animals from worms to dogs live longer, but it takes longer to study monkeys and humans.

They tested 24 people, 12 who ate a calorie-restricted diet, and 12 who dieted and also exercised five times a week for six months.

The dieters ate 25 percent less than normal, while the exercisers reduced their calorie intake by 12.5 percent and increased their physical activity to lose an extra 12.5 percent in calories.

Another 10 volunteers acted as controls. All food was provided by the university in carefully measured portions for most of the study.

The volunteers in both groups lost about 10 percent of their body weight, 24 percent of their fat mass, and 27 percent of their abdominal visceral fat. Visceral fat is packed in between the internal organs and is considered the most dangerous type of fat, linked with heart disease and diabetes.

The distribution of the fat on the body was not altered by either approach -- helping prove that there is no such thing as "spot reducing," Ravussin said in a telephone interview.

This suggests that "individuals are genetically programmed for fat storage in a particular pattern and that this programming cannot easily be overcome," he added.

Ravussin has published other studies that also dispute the idea that exercise builds muscle that helps people lose weight.

"If anything, highly trained people are highly efficient, so they burn fewer calories at rest," Ravussin said.

Dieting alone also did not appear to cause the volunteers to lose muscle mass along with fat, Ravussin's team found.

"There is a concept that if you exercise, you are going to lose less of your muscle," he said. But his team found no evidence this is true.

Ravussin believes exercise is crucial to health, however.

"For overall health, an appropriate program of diet and exercise is still the best," he said.

His team found some small suggestion that cutting 25 percent of calories by either diet or diet and exercise might extend life.

"We found that 2 of the biomarkers of aging were improved -- core temperature was 0.4 to 0.5 degrees C less," he said. "Insulin, which has been shown to be a biomarker of aging, was reduced," Ravussin said. That finding was published in the Journal of the American Medical Association last April.

 
Thanks for the replies. I assume from your replies you disagree in general with the study / article.
Does this mean that you support the following:

1. Strength training is required to prevent muscle loss while in a calorie deficit.
2. Increase in LBM increases metabolism (BMR).

What causes the body to resort catabolism of muscle rather than stored fat?
Is muscle catabolism caused more by a 1) calorie deficit 2) lack of protein 3) lack of using/working the muscle or 4) all of these ?

1. Maybe not in the beginning, but in the long run, YES
2. Increased LBM = the greater number of calories burned in a day

What causes catabolism? Your body stores fat to use a "quick" energy when it needs it. Also, your body sees unused muscles as a waste of calories. So, if you have a good amount of muscle, and starve yourself, your body will use both fat AND muscle to fuel itself instead of taking energy from just fat stores. Remember, your body wants to be as efficient as possible. If it can find a way to get around using fat stores as it's energy source, then it will use it.
 
I looked and could find not further information about this study. There is lots of stuff online about the Doctor who did the study.

If someone could find the journal article where is it published that would have (I would think) the specifics on the exercise and diet of the subjects.
 
This study ARTICLE is popping up all over the place and frankly is wearing on my nerves. I can't find the actual study and I have looked.

Honestly the study I posted give direct information to why this study is false. So if anyone wants to partake in that one, finding the other one is pointless.

I would like to note that this man works primarily with the obese so it is likely that these were obese subjects. If so guess what, not a surprise or nothing new that caloric deficit is enough for them to lose weight and they wont lose muscle.

However there is just no way this study was done on a male or female with a lower range of bodyfat (15% lower male, 20% lower female) and these were the results.
 
For what it's worth, I found this:

The Muscle-Loss Diet

January 30, 2007
A small study is getting a lot of attention the past couple of days, as do most recent studies of calorie restriction.

This Reuters report has a pretty good summary of the findings:

Eating less and exercising more are equally good at helping take off the pounds, U.S. researchers said in a study that challenges many of the popular tenets of the multibillion dollar diet and fitness industry.

Tests on overweight people show that a calorie is just a calorie, whether lost by dieting or by running, they said.

They found there is no way to selectively lose belly fat, for instance, or trim thighs. And their carefully controlled study added to evidence that adding muscle mass does not somehow boost metabolism and help dieters take off even more weight.


I haven't seen the entire study, so I can only guess at some of the reasons for the statements I just quoted.

The abstract notes that there were 24 active participants in the study, and 11 controls. They were equally divided among men and women, which means there were just six men in each of the two groups. I emphasize gender because if an exercise or weight-loss study is going to show dramatic results, it tends to be the men who'll get them. So when the researchers talk about increased muscle mass not affecting the results, it's important to realize the group they're talking about included just six men.

It's also worth noting that the "exercise" they're talking about is endurance exercise. So I'm not sure why they'd throw in a gratuitous line about how "adding" muscle mass doesn't increase metabolism, since the participants in the study clearly lost muscle mass. (I'll break down the numbers in a moment.)

And even if they'd really gained a bit of muscle, nobody thinks that the minuscule hypertrophy of slow-twitch muscle fibers seen in endurance exercise will increase metabolism outside the context of the exercise itself. You need strength training to do that, and even then you probably wouldn't see much of an effect in a mixed group of men and women. Whatever gains the men made would be canceled out by the women, who would be unlikely to gain enough muscle mass to affect their resting metabolic rates.

That said, this part is a surprise:

The volunteers in both groups lost about 10 percent of their body weight, 24 percent of their fat mass and 27 percent of their abdominal visceral fat. Visceral fat is packed in between the internal organs and is considered the most dangerous type of fat, linked with heart disease and diabetes.

The distribution of the fat on the body was not altered by either approach -- helping prove that there is no such thing as "spot reducing," Ravussin said in a telephone interview.

I don't have time to look them up this morning, but I've certainly seen studies where exercisers lost more midsection fat than non-exercisers. Maybe those studies looked at all mid-body fat, rather than visceral fat exclusively, which would explain the discrepancy.

Alwyn Cosgrove looked at the study and came to this conclusion:




The take home message is, once again, [that] steady-state aerobic exercise appears to contribute nothing to fat loss over caloric restriction alone. A good fat-loss program should include some form of caloric restriction, resistance training and some higher-intensity cardiovascular work to create a caloric deficit and ramp up metabolic demand.


To that I'd add this:

Wouldn't it be interesting to look at the participants, and see if there's any visual difference in the two groups? Does either group look healthier than they did before they lost the weight? Does the group that combined diet and exercise look fit and athletic?

I wouldn't recommend either approach -- radically cutting calories, or just dramatically cutting calories while also doing death-march endurance exercise five days a week. But I can't argue with the results -- they lost about 18 pounds on average, including about two pounds of visceral fat.

The diet-plus-exercise group lost slightly more fat -- 14 pounds, vs. just under 13 for the diet-only folks. But that's still a surprisingly good result for the people who were starved. To lose 18 pounds in six months, 10 percent of total body weight, and only lose five pounds of muscle is a damned good trick.

But in a way, that was the easy part. The hard part comes over the next six months, when they try to continue restricting diet and/or exercising at those levels.

Posted by LouSchuler at January 30, 2007 07:03 AM
 
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