Glutamine

The only supplements i usually use are whey, creatine, and a multi. My friend gave me tub of Glutamine, whats your opinion on it? How or when do you take it?
 
You take it when you are a burn victim, AIDS patient, or Cancer patient.

Seriously. No study has shown supplmental l-glutamine to be beneficial. Marketing will tell you it speeds recovery and increases fat loss.

They lie.
 
No, because glutamine isn't really a 'protein'. protein is made up from amino acids. Complete proteins contain all the essential amino acids. Incomplete proteins don't.

Glutamine is just one amino acid, and since increased dietary intake of glutamine doesn't benefit you, its not the same as 'contributing to the total protein in the shake'.

it won't hurt you either, but its just not going to do anything useful, and it will add grit to your shake much like creatine does.
 
i understand your point about it not helping out with anything, but i dont understand how it cant add to the total protein. I doesent make sence cause anytime you add a singular amino to the mix of other proteins, it should add to the total.
 
Think of amino acids like bricks, and a protein molecule as a whole house.

throwing bricks in your living room doesn't give you a bigger living room. it just gives you bricks in the living room.

furthermore the body is going to tear apart the protein and use it for different things...so you still only have extra bricks, which science has proven doesn't help out the average trainee/athlete.
 
Always do your own research......

L-Glutamine benefits:

prevents muscle breakdown (which is a process known as catabolizing)
helps produce new muscle via protein synthesis (muscle is created from proteins)
enhance immune system function
it may improve mental sharpness (one of the l-glutamine benefits is that it is converted to glutamic acid in the brain, which in turn promotes the synthesis of GABA, which is a crucial neurotransmitter).
increase wound healing
can boost your body's production of growth hormones
it helps promote a healthy intestinal tract..
We expend glutamine quickly.. a little bit of stress- gone.
Any protein that really works - you notice an actually difference -solid muscle, better recovery - will have 3 - 5g of gluta per serving.
 
This is probably spam, but can you link to a single study that has showed glutamine supplementation to be beneficial in healthy subjects?
 
Everything has its uses and abuses.

glutamine article said:
The only safe situation for glutamine use is in the vigorous athlete. Glutamine is used as a muscle fuel, so that vigorous exercise will consume most of the glutamine before it can accumulate in the brain. I would still avoid long-term use in high doses. I would caution readers to avoid excess glutamine, especially in the above named conditions and situations.

articles.mercola.com/sites/articles/archive/2004/05/01/glutamine.aspx
 
I can't see a single reference listed and I have never seen anyone reporting serious neural damage following glutamine use.

When glutamate is released in synapses it is taken up again by glia cells by active transport (requiring ATP). If there is not enough ATP (for example because of a stroke) the glutamate will go out of the glia cells again, activate receptors and have ions transported into the neuron. The receptor used transports a lot of ions so there will be too much which can cause the cell to die. However, for this to happen there must be a loss of ATP.. it doesn't matter if you have a lot of glutamate in the glia or neuron, it needs to get outside from a loss of ATP. Maybe if you take glutamate you could get more damage once ATP is lost, but the glutamate alone shouldn't do anything.
He mentions two studies but no references.

I can't comment on the other conditions as I don't know anything about them, like pregnancy, etc. But if you're healthy, I see no reason why glutamate should be dangerous. However, you shouldn't take it anyway as it gives you no real benefit except for in a few special conditions like burns, etc.
 
Feel free to contact the guy for references. I can see an article on BB.com The Effects Of Glutamine Supplementation On Athletic Performance! - Chris Goulet where tonnes of references are given it should come up if you do a search for "glutamine supplementation" on google.

Research shows that glutamine supplementation can not only help an athlete prevent illness and prevent catabolism of muscle tissue, but it can actually boost growth hormone levels, enhance glycogen storage, and hydrate muscle cells - three components important in protein synthesis or energy metabolism (Antonio and Street, 1999).
 
No, because glutamine isn't really a 'protein'. protein is made up from amino acids. Complete proteins contain all the essential amino acids. Incomplete proteins don't.

Glutamine is just one amino acid, and since increased dietary intake of glutamine doesn't benefit you, its not the same as 'contributing to the total protein in the shake'.

it won't hurt you either, but its just not going to do anything useful, and it will add grit to your shake much like creatine does.

It does not sound good if so.
 
Glutamine is a non-essential amino acid, acceptation it can be produced by the physique and is complex in a array of metabolic processes. Glutamine has afresh been re-classified as a conditionally capital amino acid. This agency that while the physique can accomplish glutamine, beneath acute concrete accent the appeal for glutamine exceeds the body's adeptness to amalgamate it.

_________
 
I'll paste something I wrote about glutamine on another forum in here:

Not a big fan of glutamine either. It had a lot of theoretical support (specially with regards to the immune system after exercise), which is why it was claimed as being a good supplement before anyone actually tested it. But when they started testing it they didn't find anything in healthy people as far as performance increases go.
Here's a link to a free review article on glutamine supplementation:

The only thing that really comes close to being evidence for an anabolic effect is that GH is increased after exercise with glutamine supplementation, but GH doesn't really help with skeletal muscle anabolism.

There isn't a whole lot of studies comparing glutamine with placebo in a resistance training study, thought.. I've only found one, which found no effect.

and then this:

Glutamine is a very abundant amino acid in the body, but levels do drop after exercise, but it's probably not enough to really make a huge difference on the immune system. However, I think some studies have seen some positive effects after very heavy endurance exercise (while others haven't). The thing is, that you have to compare it to other protein/amino acid sources. If you take glutamine and whey after your work out, will the glutamine help any on top of the whey, or will you get all you need from the whey? If you take glutamine on top of whey after a work out, will that help any more than simply taking more whey? If it doesn't then you just have to find out which one is cheaper (I have no idea what glutamine supps cost)

This study found an increase in protein synthesis, but what if you had compared it to regular whey or another cheap protein product providing a similar amount of nitrogen? In addition, they measured whole body protein synthesis and not protein synthesis of muscle proteins.
 
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