DeX said:
Not to mention that the quads have been found to have a lot of TYPE II muscle fibers, so fairly high intensity is needed...
I'd be interested to see a study or reference on this one.
Otherwise, very good advice already.
Apart from reading on elitefts, here's the basics on squat for noobs:
Get some light free squat form work as a first thing (after warm-up, of course). With 4x6 or, say, 3x5 or 5x5, and about 1-2 min. rest, without going anywhere near to failure, you can't go wrong.
Squat form: about a shoulder width stance, lower back and glutes arched maximally. Get the bar up to your neck, with a narrow grip, elbows to the front. Try to split the floor to your sides with your legs. Try to get your glutes between your legs when you dive. In the consentric portion of the lift, i.e. when you come up, arch your upper body also. Get your chest up high, straighten your neck, brace your shoulder blades together and down, and get your elbows to sides of your torso. Try to fire with your glutes. I assure you they won't grow too big and you'll end up not getting knee and low back problems as easily as a usual gym rat training with machines. When you're getting down, i.e. in the eccentric portion of the lift, don't arch your upper body. Look a bit down. And remember: before the rep, get your belly totally full of air and flex your abs as if you were getting ready to receive a punch.
Consentrate on as many points as you can at a time without going nuts.