Estuve mirando unos estudios recientes sobre el efecto en nuestro organismo de la arginina. Son muy largos , pero merece la pena leerlos y sacar una conclusion. Lo que si está demostrado , es que mejora el sistema inmunitario e interfiere en el desarrollo del cancer.Tambien comenta que a la larga podría provocar problemas de impotencia.
"Nitric oxide is toxic at high physiological concentration where it appears to function as a cellular effector molecule that mediates both cytostatic and cytotoxic effect." [1]
"NO is generated in the course of inflammatory and immune reactions, both by macrophages and by neutrophils. The role of these cells is quite extensive, and includes phagocytic and non-phagocytic destruction of foreign or damaged cells. These processes involve the production of large quantities of NO, which is cytotoxic." [1]
"Although NO can be cytotoxic to tumour cells (as it is to other cells), it can also act as a carcinogen." [2]
"NO, a chemical radical, and its toxic derivatives can cause DNA damage and cell death in a variety of cell types. NO also has the ability to directly modify intracellular targets such as proteins and lipid-peroxidation products. NO produces cytotoxicity at high concentrations, whereas NO at lower concentrations may have the opposite effect and protect against apoptotic cell death from various stimuli. Therefore, regulation of NO production is vital for both cell survival and genome integrity. DNA damage triggers p53 protein accumulation, which produces either growth arrest or apoptosis. Exposure of cells to high NO concentrations causes DNA damage and apoptosis, and recent results have shown that NO stimulates p53 accumulation and p53-mediated apoptosis." [3]
[1] This URL has been removed!
[2] This URL has been removed!
[3] Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice -- Ambs et al. 95 (15): 8823 -- Proceedings of the National Academy of Sciences
"Nitric oxide is toxic at high physiological concentration where it appears to function as a cellular effector molecule that mediates both cytostatic and cytotoxic effect." [1]
"NO is generated in the course of inflammatory and immune reactions, both by macrophages and by neutrophils. The role of these cells is quite extensive, and includes phagocytic and non-phagocytic destruction of foreign or damaged cells. These processes involve the production of large quantities of NO, which is cytotoxic." [1]
"Although NO can be cytotoxic to tumour cells (as it is to other cells), it can also act as a carcinogen." [2]
"NO, a chemical radical, and its toxic derivatives can cause DNA damage and cell death in a variety of cell types. NO also has the ability to directly modify intracellular targets such as proteins and lipid-peroxidation products. NO produces cytotoxicity at high concentrations, whereas NO at lower concentrations may have the opposite effect and protect against apoptotic cell death from various stimuli. Therefore, regulation of NO production is vital for both cell survival and genome integrity. DNA damage triggers p53 protein accumulation, which produces either growth arrest or apoptosis. Exposure of cells to high NO concentrations causes DNA damage and apoptosis, and recent results have shown that NO stimulates p53 accumulation and p53-mediated apoptosis." [3]
[1] This URL has been removed!
[2] This URL has been removed!
[3] Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice -- Ambs et al. 95 (15): 8823 -- Proceedings of the National Academy of Sciences
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